Characterization Of Adverse Drug Reactions With Emphasis On The Molecular Basis Of Drug Hypersensitivity Reactions, And Also The Development Of Medicinal Products From Natural Sources
I am currently employed as a Lecturer in the Department of Pharmacology and Toxicology at the Faculty of Pharmaceutical Sciences University of Ilorin. I currently teach undergraduate students in Pharmacy and graduate students’ pharmacology.
The primary focus of my research is the characterization of adverse drug reactions with emphasis on the molecular basis of drug hypersensitivity reactions, and also the development of medicinal products from natural sources. I have previously been able to modify existing methods to detect drug-specific B-cell responses in piperacillin tolerant and hypersensitive patients with Cystic Fibrosis (CF). I also established a profile for the generation of piperacillin-specific IgG producing CD19+CD27+ cells and characterised piperacillin-specific T-cell responses and IgG antibodies in CF patients’ cohort. I thus took the first steps in exploring the relationship between antibodies and T cells in hypersensitivity reactions.
Currently my research group has just received funding from the Nigerian Tertiary Education Trust Fund Academic Staff Training (TETFUND) for the conduct of a research on the Molecular Events Underpinning Cutaneous Manifestations of Beta lactam and Carbamazepine Hypersensitivity Reactions in with a focus on patients of African descent to be conducted in Nigeria.